Efficacy of Quadrivalent HPV Vaccine against HPV Infection and Disease in Males
نویسنده
چکیده
Anna R. Giuliano, Ph.D., Joel M. Palefsky, M.D., Stephen Goldstone, M.D., Edson D. Moreira, Jr., M.D., Mary E. Penny, M.D., Carlos Aranda, M.D., Eftyhia Vardas, M.D., Harald Moi, M.D., Heiko Jessen, M.D., Richard Hillman, M.D., Yen-Hwa Chang, M.D., Daron Ferris, M.D., Danielle Rouleau, M.D., Janine Bryan, Ph.D., J. Brooke Marshall, Ph.D., Scott Vuocolo, Ph.D., Eliav Barr, M.D., David Radley, M.S., Richard M. Haupt, M.D., and Dalya Guris, M.D.
منابع مشابه
Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males.
A small number of HPV types are related to a majority of HPV-related neoplastic lesions in humans. High-risk types such as HPV 16 and 18 are most often implicated, although other oncogenic and non-oncogenic HPV types can cause disease in men. The efficacy of the quadrivalent HPV vaccine (qHPV) against external genital lesions and intra-anal disease related to HPV in men has been demonstrated. T...
متن کاملHPV vaccine against HPV infection and disease in males.
BACKGROUND Infection with human papillomavirus (HPV) and diseases caused by HPV are common in boys and men. We report on the safety of a quadrivalent vaccine (active against HPV types 6, 11, 16, and 18) and on its efficacy in preventing the development of external genital lesions and anogenital HPV infection in boys and men. METHODS We enrolled 4065 healthy boys and men 16 to 26 years of age,...
متن کاملCost-Effectiveness Evaluation of Quadrivalent Human Papilloma Virus Vaccine for HPV-Related Disease in Iran
Human Papilloma Virus (HPV) vaccine recently has been added to the Iran Drug List, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term benefit ...
متن کاملCost-Effectiveness Evaluation of Quadrivalent Human Papilloma Virus Vaccine for HPV-Related Disease in Iran
Human Papilloma Virus (HPV) vaccine recently has been added to the Iran Drug List, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term benefit ...
متن کاملOverview of the clinical development and results of a quadrivalent HPV (types 6, 11, 16, 18) vaccine.
BACKGROUND Human papillomaviruses (HPVs) play an obligatory role in cervical cancer development. Thus, immunization of women using a prophylactic vaccine against the most common high-oncogenic risk types (e.g., HPV 16 and 18) and HPV 6 and 11, which contribute to development of low-grade cervical lesions and cause most anogenital warts, represents a logical primary prevention strategy. PERSPE...
متن کاملProphylactic efficacy of a quadrivalent human papillomavirus (HPV) vaccine in women with virological evidence of HPV infection.
BACKGROUND A quadrivalent (types 6, 11, 16, and 18) human papillomavirus (HPV) L1 virus-like-particle (VLP) vaccine has been shown to be 95%-100% effective in preventing cervical and genital disease related to HPV-6, -11, -16, and -18 in 16-26-year-old women naive for HPV vaccine types. Because most women in the general population are sexually active, some will have already been infected with >...
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